Per Øystein Sakariassen

Field of work

I have a background in cancer research from the University of Bergen where I researched malignant brain cancer. Furthermore, I graduated from UiB in 2001 with the title "The Development of Angiostatin Secreting Cell Lines for the Therapy of Gliomas". In 2007 I did my dissertation at UiB where the title of the dissertation was "Cancer Stem Cells and Angiogenesis in Brain Tumors - Biological Mechanisms During Tumor Progression".

Qualifications:

Molecular biological techniques such as RT-PCR, Western blot and immunocyto/-histochemistry. Cell biology, cell culture, tumor biology, experimental animals course class C. Anatomy and physiology.

I also work professionally with photo/video, live-streaming and 3D graphics.

Selected publications:

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma. Tardito S, Oudin A, Ahmed SU, Fack F, Keunen O, Zheng L, Miletic H, Sakariassen PØ, Weinstock A, Wagner A, Lindsay SL, Hock AK, Barnett SC, Ruppin E, Mørkve SH, Lund-Johansen M, Chalmers AJ, Bjerkvig R, Niclou SP, Gottlieb E. Nat Cell Biol. 2015 Dec; 17 (12): 1556-68. doi: 10.1038 / ncb3272. Epub 2015 Nov 23.

CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Wang J, Sakariassen PØ, Tsinkalovsky O, Immervoll H, Bøe SO, Svendsen A, Prestegarden L, Røsland G, Thorsen F, Stuhr L, Molven A, Bjerkvig R, Enger PØ. Int J Cancer. 2008 Feb 15; 122 (4): 761-8. doi: 10.1002 / ijc.23130.

Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Sakariassen PØ, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, Sminia P, Sundlisaeter E, Misra A, Tysnes BB, Chekenya M, Peters H, Lende G, Kalland KH, Øyan AM, Petersen K, Jonassen I , van der Kogel A, Feuerstein BG, Terzis AJ, Bjerkvig R, Enger PØ. Proc Natl Acad Sci U S A. 2006 Oct 31; 103 (44): 16466-71. doi: 10.1073 / pnas.0607668103. Epub 2006 Oct 20.

* = 1st author.