Research and development projects

This research projects aims at increasing knowledge about how different forms of physical exercise can affect biochemical, molecular and cell biological parameters in the body, in health / disease and for best recovery / performance.

Projects

• microRNAs as biomarkers of training load and recovery in well-trained cyclists.
  

The role of gene variants in the normal development of the pancreas and insulin production are characterized in maturity-onset diabetes of the young (MODY), aiming to develope precision medicine for inherited diabetics. Laboratory methods used are cell culturing and animal models (zebrafish).

Projects

• Gene-editing HNF1B in zebrafish to decipher disease mechanisms by MODY5.
• Functional investigations of HNF4A variants related to various glycemic phenotypes.

More to come...

Monocytes consist of classical, intermediate, and non-classical monocytes. In haematological malignancies, such as multiple myeloma and acute myeloid leukaemia, monocytes are affected by both the disease itself and the treatment patients receive.

The overall aim of this project was to explore monocyte subpopulations in clinical settings of haematological malignancies by (i) elucidating the important pre-analytical factors to properly identify the subsets, (ii) monitoring monocyte regeneration after stem cell transplantation in patients with haematological malignancies, and (iii) investigating the effects of immunomodulatory drugs on metabolism and cytokine secretion.

Projects

• Immunomodulatory Drugs Alter the Metabolism and the Extracellular Release of Soluble Mediators by Monocytes. (Concluded)
• Genomic blood typing by liquid array diagnostics (LAD)
• Investigation of non-BCR-ABL dependent resistance in Chronic Myeloid Leukemia (CML)
• Parabener og in vitro effekter på T celler (concluded)
  • Investigation of non-BCR-ABL dependent resistance in Chronic Myeloid Leukemia (CML)
  • Parabener og in vitro effekter på T celler (concluded
    • Genomic blood typing by liquid array diagnostics (LAD)
    • Investigation of non-BCR-ABL dependent resistance in Chronic Myeloid Leukemia (CML)
    • Parabener og in vitro effekter på T celler (concluded

BIOMARG has had several development and innovation projects for bioengineering education which have resulted, among other things, in the establishment of the website ePraksis.no, which won the national Education Quality Award in 2018.

Here are some of our ongoing research and development projects: 

• Nasjonalt systematisk samarbeid for videreutvikling av arbeidslivsrelevans i bioingeniørutdanningene.
• Produksjon av caser innen Transfusjonsmedisin (digitaliseringsprosjekt)
• BioTriCK– Biomedical laboratory sciences Triangular Centre of Knowledge
• EduMedLab: Education for Medical Laboratories
• EduGameLab: Digital games for learning in the BLS education