KJETEK
The KJETEK research group mainly addresses issues within medicinal chemistry and environmentally friendly energy applications.
Common for the projects is that they combine organic-, inorganic- and physical chemistry and materials science, with focus on health, environment and sustainability. For example, we want to use environmentally friendly chemicals, reduce waste and optimize the various chemical processes involved in the laboratory work.
The research areas include:
- Synthesis, analysis and studying properties of organic and inorganic compounds.
- Production of components and systems based on these compounds for various applications, such as electrodes and electrolytes for batteries and pharmaceutical components.
- Chemistry didactics and communication.
We use the institute's laboratories and instruments, such as UHPLC, GC-MS, NMR, IR, UV, Langmuir, TG-DTA, ICP-OES, EIS, to analyze the products and develop laboratory procedures and analytical methods. In addition, we actively seek to develop a national and international network with collaborative projects in knowledge exchange and the use of experimental instrumentation.
The research is actively used in teaching programs for modernization. It is used for developement of laboratory subjects and parts of the projects are given as bachelor and master theses.
Members
Associated member
Research projects
Featured publications
Introduction of NMR to biomedical laboratory scientists through a laboratory exercise; synthesis, structure determination and quantization of aspirin using a 1 HNMR bench-top instrument. M. K. Leiren and S. Steinkopf, World Journal of Chemical Education 2022 ;Volume 10.(1) pp. 8-19.
Published articles based on Bachelor theses
pH Dependent Drug Interaction with Glycerophospholipid Monolayers Studied by the Langmuir Technique, Steinkopf, S., Simeunović, A., Bustad, H. J., Ngo, T. H., Sveaass, H., Gjerde, A. U. and Holmsen, H. Biophys. Chem. 2010, 152, 65-73.
The Psychotropic Drug Olanzapine (Zyprexa®) Increases the Area of Acid Glycerophospholipid Monolayers, S. Steinkopf, A. K. Schelderup, H. L. Gjerde, J. Pfeiffer, S. Thoresen, A. Underhaug Gjerde and H. Holmsen Biophys. Chem. 134,
Bachelor theses
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Study and Optimization for a Synthesis of One Building Block to the Anti-Cancer Molecules Avrainvillamid and Stephacidin B, J. H. Flornes, T. M. Sneve Aakerblad, C. M. Bauge B.S. thesis, 2021.
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Assessment of the Greenness of the Syntheses of the Anti-Malarial Drugs Chloroquine, Hydroxychloroquine and Quinacrine, I. Steinkjellå, J. Anglevik, S. N. Morlandstø B.S. thesis, 2020.
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An Alternative Synthesis of the Anti-Cancer Drug “Bexarotene”, P. A. Asheim, T. S. Henriksen, J. Midtbø B. S. thesis, 2019.
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Method Development and Quantitative Determination of Biogenic Amines in Food and Drink by UHPLC. Z. Karkouchia,T. H. Clementsen, M. H. Clementsen B. S. thesis, 2017.