Førsteamanuensis

Trond Brattelid

Arbeids- og kompetanseområde

Jeg har erfaring fra grunn- og anvendt forsking innen fysiologi, farmakologi og biomedisin og adminisrasjon som forskningsrådgivning.

Min allsidige faglige bakgrunn inkluderer akvakulturutdanning ved Høgskolesenteret i Bodø, Cand. scient. i komparativ fysiologi (miljøfysiologi), med hovedfagsoppgave innen respirasjonsfysiologi ved Universitetet i Bergen (UiB) og Dr. philos. grad i molekylær hjertebiologi/farmakologi/fysiologi fra Farmakologisk institutt, Universitetet i Oslo (UiO).

Etter gjennomført dr. philos. grad ved UiO med fokus på endringer i genekspresjon, reseptorfunksjon og kontraktilitet ved hjertesvikt med bruk av humant hjertevev og dyremodeller, har jeg forskererfaring som post doktor ved Biomedisinsk institutt, UiB og forsker ved Nasjonalt senter for ernæring og sjømatforskning.

Underviser i

Har emneansvar for:

BIO101 Danning og akademisk handverk

BIO206 Medisinsk laboratorieteknologi III

BIO305 Profesjonsetikk og kommunikasjon

Har veilederansvar i:

BIO207 Ekstern praksis 1

BIO350 Bacheloroppgave - Bioingeniør

Har hatt emneansvar for:

BIO201 Hematologi og Immunologi

Forskar på

Ut over farmakologisk forskning i molekylær hjertebiologi/fysiologi kan forskningsaktiviteten oppsummeres med evaluering av effekten av ernæring og miljøgifter på biologisk utvikling og livsstilsykdommer i ulike dyremodeller (innavlede, villtyper og «knoc out») med blant annet fokus på endringer i DNA og miRNA ekspresjon og epi-genetikk.

Publikasjonar

  • Gir bioingeniørutdanningene gode redskaper for å håndtere og forebygge krenkelser?

    Lie-Jensen, Anette Christensen, Brattelid, Trond, Neslein, Inger-Lise F., Ersvær, Elisabeth, Alm, Bente, Tunsjø, Hege (2023)
  • Improving animal research: PREPARE before you ARRIVE

    Smith, Adrian, Clutton, R. Eddie, Lilley, Elliot, Hansen, Kristine Eraker Aasland, Brattelid, Trond (2018)
  • PREPARE: guidelines for planning animal research and testing

    Smith, Adrian, Clutton, R. Eddie, Lilley, Elliot, Hansen, Kristine Eraker Aasland, Brattelid, Trond (2017)
  • Macronutrient composition determines accumulation of persistent organic pollutants from dietary exposure in adipose tissue of mice

    Myrmel, Lene Secher, Fjære, Even, Midtbø, Lisa Kolden, Bernhard, Annette, Petersen, Rasmus Koefoed, Sonne, Si Brask (2016)
  • Marine fatty acids aggravate hepatotoxicity of α-HBCD in juvenile female BALB/c mice

    Bernhard, Annette, Berntssen, Marc, Haldorsen, Anne-Katrine L., Alvheim, Anita Røyneberg, Myrmel, Lene Secher, Fjære, Even (2016)
  • A water-soluble extract of chicken reduced plasma triacylglycerols, but showed no anti-atherosclerotic activity in apoE<sup>-/-</sup> mice

    Pedersen, Rita, Brattelid, Trond, SKORVE, JON, Nygård, Ottar Kjell, Nordrehaug, Jan Erik, Berge, Rolf Kristian (2015)
  • The Role of Persistent Organic Pollutants in Induction of Endoplasmic Reticulum Stress in Hepatocytes in vitro and in vivo

    Heggland, Erna Irene, Brattelid, Trond, Tronstad, Karl Johan, Bernhard, Annette (2015)
  • Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice

    Midtbø, Lisa Kolden, Borkowska, Alison G., Bernhard, Annette, Rønnevik, Alexander, Lock, Erik-Jan, Fitzgerald, Michael L. (2015)
  • B-type natriuretic peptide expression and cardioprotection is regulated by Akt dependent signaling at early reperfusion

    Breivik, Lars Ertesvåg, Jensen, Andreas, Guvåg, Steinar, Aarnes, Eva-Katrine, Aspevik, Anne, Helgeland, Erik (2015)
  • Hypolipidemic effect of dietary water-soluble protein extract from chicken: impact on genes regulating hepatic lipid and bile acid metabolism

    Vik, Rita, Bjørndal, Bodil, Bohov, Pavol, Brattelid, Trond, Svardal, Asbjørn M., Nygård, Ottar (2014)
  • The cardioprotective effect of the modern Atlantic salmon - dietary spillover from fish

    Bernhard, Annette, Rasinger, Josef Daniel, Mitdbø, LK, Myrmel, Lene Secher, Torstensen, Bente Elisabeth, Kristiansen, K (2014)
  • The role of seafood intake in late pregnancy on mercury levels in hair of mothers and their infants

    Høgden, H.A.R, Bernhard, Annette, Markhus, Maria W., Amlund, Heidi, Haldorsen, Anne-Katrine L., Frøyland, Livar (2014)
  • Hypolipidemic effect of dietary water-soluble protein extract from chicken: impact on genes regulating hepatic lipid and bile acid metabolism

    Vik, Rita, Bjørndal, Bodil, Bohov, Pavol, Brattelid, Trond, Svardal, Asbjørn M., Nygård, Ottar (2014)
  • A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in apoE-deficient mice

    Parolini, Cinzia, Vik, Rita, Busnelli, Marco, Manzini, Stefano, Holm, Sverre, Bjørndal, Bodil (2014)
  • Environmental contaminants in mother and child - Is there a correlation between mothers seafood intake and levels of environmental persistent organic contaminants in mother and child at 3, 6 and 12 months post partum

    Sørli, Kaja, Barnung, R. B., Markhus, Maria W., Araujo, Pedro, Rasinger, Josef Daniel, Malde, Marian Kjellevold (2014)
  • Krill oil versus fish oil in modulation of inflammation and lipid metabolism in mice transgenic for TNF-α

    Vigerust, Natalya Filipchuk, Bjørndal, Bodil, Bohov, Pavol, Brattelid, Trond, Svardal, Asbjørn M., Berge, Rolf Kristian (2013)
  • Intake of Farmed Atlantic Salmon Fed Soybean Oil Increases Insulin Resistance and Hepatic Lipid Accumulation in Mice

    Ibrahim, Mohammad Madani, Myrmel, Lene Secher, Liisberg, Ulrike, Liland, Nina Sylvia, Torstensen, Bente Elisabeth, Brattelid, Trond (2013)
  • alpha HBCD: Effect or no effect - A matter of diet?

    Bernhard, Annette, Myrmel, Lene Secher, Kolden Mitbø, Lisa, Ibrahim, Mohammad Madani, Rasinger, Josef Daniel, Torstensen, Bente Elisabeth (2013)
  • An immunomodulating fatty acid analogue targeting mitochondria exerts anti-atherosclerotic effect beyond plasma cholesterol-lowering activity in apoE(-/-) mice

    Vik, Rita, Busnelli, Marco, Parolini, Cintia, Bjørndal, Bodil, Bohov, Pavol, Holm, Sverre (2013)
  • Fish Oil and the Pan-PPAR Agonist Tetradecylthioacetic Acid Affect the Amino Acid and Carnitine Metabolism in Rats

    Bjørndal, Bodil, Brattelid, Trond, Strand, Elin, Vigerust, Natalya Filipchuk, Svingen, Gard Frodahl Tveitevåg, Svardal, Asbjørn M. (2013)
  • Net production of Atlantic salmon (FIFO, Fish in Fish out &lt; 1) with dietary plant proteins and vegetable oils

    Liland, Nina Sylvia, Rosenlund, Grethe, Berntssen, Marc, Brattelid, Trond, Madsen, Lise, Torstensen, Bente Elisabeth (2013)
  • Intake of farmed atlantic salmon fed soybean oil increases insulin resistance and hepatic lipid accumulation in mice

    Midtbø, Lisa Kolden, Ibrahim, Mohammad Madani, Myrmel, Lene Secher, Aune, Ulrike Liisberg, Alvheim, Anita Røyneberg, Liland, Nina Sylvia (2013)
  • Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet

    Bjørndal, Bodil, Vik, Rita, Brattelid, Trond, Vigerust, Natalya Filipchu, Burri, Lena, Bohov, Pavol (2012)
  • The Cardiac Ventricular 5-HT4 Receptor Is Functional in Late Foetal Development and Is Reactivated in Heart Failure

    Brattelid, Trond, Qvigstad, Eirik, Moltzau, Lise Roman, Bekkevold, Silje Veslemøy, Sandnes, Dagny Lise, Birkeland, Jon Arne (2012)
  • Cerebral gene expression and neurobehavioural responses in mice pups exposed to methylmercury and docosahexaenoic acid through the maternal diet

    Jayashankar, Shalini, Glover, Chris, Folven, Kristin Ingvaldsen, Brattelid, Trond, Hogstrand, Christer, Haldorsen, Anne-Katrine L. (2012)
  • Quantification of GPCR mRNA Using Real-Time RT-PCR

    Brattelid, Trond, Levy, Finn Olav (2011)
  • Cerebral gene expression in response to single or combined gestational exposure to methylmercury and selenium through the maternal diet

    Jayashankar, Shalini, Glover, Chris, Folven, Kristin Ingvaldsen, Brattelid, Trond, Hogstrand, Christer, Haldorsen, Anne-Katrine L. (2011)
  • Cerebral gene expression and neurobehavioural development after perinatal exposure to an environmentally relevant polybrominated diphenylether (BDE47)

    Haave, Marte, Folven, Kristin Ingvaldsen, Carroll, Thomas, Glover, Chris, Heegaard, Einar, Brattelid, Trond (2011)
  • Normalization strategy is critical for the outcome of miRNA expression analyses in the rat heart

    Brattelid, Trond, Aarnes, Eva-Katrine, Helgeland, Erik, Guvåg, Steinar, Eichele, Heike, Jonassen, Anne K. (2011)
  • Fish consumption reduces transfer of BDE47 from dam to murine offspring

    Haave, Marte, Bernhard, Annette, Folven, Kristin Ingvaldsen, Brattelid, Trond, Lundebye-Haldorsen, Anne Katrine (2011)
  • Long-term effects of environmentally relevant doses of 2,2 ',4,4 ',5,5 ' hexachlorobiphenyl (PCB153) on neurobehavioural development, health and spontaneous behaviour in maternally exposed mice

    Haave, Marte, Bernhard, Annette, Jellestad, Finn Konow, Heegaard, Einar, Brattelid, Trond, Lundebye, Anne-Katrine (2011)
  • Reference gene alternatives to Gapdh in rodent and human heart failure gene expression studies

    Brattelid, Trond, Winer, Lisbeth Hagen, Levy, Finn Olav, Liestøl, Knut, Sejersted, Ole M, Andersson, Kristin Brevik (2010)
  • Beskyttende Effekt av Insulinterapi ved Iskemisk-Reperfusjon - effekten av insulin på mRNA-nivået til HIF-1α og apelin

    Johansen, Mari, Brattelid, Trond, Jonassen, Anne K. (2008)
  • Allicin - Ekstrahert fra hvitløk (Allium sativum) Beskytter hjertet under hypoksi og ved reoksygenering

    Johannessen, Pål Espen, Brattelid, Trond, Jonassen, Anne K. (2008)
  • MicroRNAs and the Ischaemic Heart - Novel Regulation of MicroRNAs at Reperfusion in Response to Insulin Therapy

    Aarnes, Eva-Katrine, Jonassen, Anne K., Brattelid, Trond (2008)
  • Effects of treatment with a 5-HT4 receptor antagonist in heart failure

    Birkeland, Jon Arne, Sjaastad, Ivar, Brattelid, Trond, Qvigstad, Eirik, Moberg, Enrica Ratti, Krobert, Kurt Allen (2007)
  • Expression of mRNA encoding G protein-coupled receptors involved in congestive heart failure : A quantitative RT-PCR study and the question of normalisation

    Brattelid, Trond, Tveit, Kristine, Birkeland, Jon Arne, Sjaastad, Ivar, Qvigstad, Eirik, Krobert, Kurt Allen (2007)
  • Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle

    Brattelid, Trond, Qvigstad, E, Birkeland, Jan Magne, Birkeland, Jon Arne, Swift, F, Bekkevold, SVS (2007)
  • Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle

    Brattelid, Trond, Qvigstad, Eirik, Birkeland, Jon Arne, Swift, Fredrik, Bekkevold, SVS, Krobert, Kurt Allen (2006)
  • Insulin therapy appears to involve PKC and NFkB signaling when administered at reperfusion

    Tiron, CE, Kanhema, T, Kanhema, Tambudzai, Guvag, S, Brattelid, T, Mjøs, Ole Danbolt (2006)
  • Normalization genes for gene expression studies in myocardium from mice, rats and humans

    Brattelid, Trond, Winer, Lisbeth Hagen, Sejersted, Ole M, Andersson, Kristin Brevik (2006)
  • Induction of functional serotonin 5-HT2A and 5-HT4 receptors in the acute failing cardiac ventricle

    Qvigstad, Eirik, Sjaastad, Ivar, Brattelid, Trond, Nunn, Caroline, Swift, Fredrik, Birkeland, Jon Arne (2006)
  • Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle

    Brattelid, Trond, Qvigstad, Eirik, Birkeland, Jon Arne, Swift, Fredrik, Bekkevold, Silje Veslemøy, Krobert, Kurt Allen (2006)
  • The 5-HT4 receptor - a foetal gene reactivated in heart failure?

    Brattelid, Trond, Bekkevold, Silje Veslemøy, Qvigstad, Eirik, Moltzau, Lise Roman, Sandnes, Dagny Lise, Birkeland, Jon Arne (2006)
  • Treatment with a 5-HT4 serotonin receptor antagonist improves function of the failing heart

    Birkeland, Jon Arne, Sjaastad, Ivar, Brattelid, Trond, Qvigstad, Eirik, Moberg, Enrica Ratti, Krobert, Kurt Allen (2006)
  • Treatment with a 5-HT4 serotonin receptor antagonist improves function of the failing heart

    Birkeland, Jon Arne, Sjaastad, Ivar, Brattelid, Trond, Qvigstad, Eirik, Moberg, Enrica Ratti, Krobert, Kurt Allen (2006)
  • The 5-HT4 receptor - a foetal gene reactivated in heart failure?

    Brattelid, Trond, Bekkevold, Silje Veslemøy, Qvigstad, Eirik, Moltzau, Lise Roman, Sandnes, Dagny Lise, Birkeland, Jon Arne (2006)
  • Characterisation and function of a novel serotonin receptor and the role of serotonin receptors in heart failure

    Brattelid, Trond (2006)
  • Rationale for treatment of heart failure by blockade of ventricular serotonin receptors appearing in heart failure

    Qvigstad, Eirik, Brattelid, Trond, Sjaastad, Ivar, Molenaar, P., Birkeland, Jon Arne, Andressen, Kjetil Wessel (2005)
  • Induction of a 5-HT4 receptor-mediated inotropic response to serotonin in failing ventricular cardiomyocytes

    Birkeland, Jon Arne, Qvigstad, Eirik, Sjaastad, Ivar, Brattelid, Trond, Krobert, Kurt Allen, Sejersted, Ole M (2005)
  • Treatment of heart failure by blockade of ventricular myocardial serotonin receptors appearing in heart failure

    Qvigstad, Eirik, Birkeland, Jon Arne, Sjaastad, Ivar, Brattelid, Trond, Andressen, Kjetil Wessel, Krobert, Kurt Allen (2005)
  • Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart

    Qvigstad, Eirik, Sjaastad, Ivar, Brattelid, Trond, Nunn, Caroline, Swift, Fredrik, Birkeland, Jon Arne (2005)
  • Prucalopride is a partial agonist through human and porcine atrial 5-HT4 receptors: comparison with recombinant human 5-HT4 splice variants

    Krobert, Kurt Allen, Brattelid, Trond, Levy, Finn Olav, Kaumann, Alberto Julio (2005)
  • Appearance of a ventricular 5-HT4 receptor-mediated inotropic response to serotonin in heart failure

    Qvigstad, Eirik, Brattelid, Trond, Sjaastad, Ivar, Andressen, Kjetil Wessel, Krobert, Kurt Allen, Birkeland, Jon Arne (2005)
  • Normalization genes for heart failure myocardium in mice, rats and humans

    Brattelid, Trond, Winer, Lisbeth Hagen, Sejersted, Ole M, Andersson, Kristin Brevik (2005)
  • The alpha1-AR mediated activation of NKCC in rat cardiomyocytes involves ERK dependent phosphorylation of the cotransporter

    Andersen, Geir Øystein, Skomedal, Tor, Enger, Mette, Fidjeland, Astrid, Brattelid, Trond, Levy, Finn Olav (2004)
  • Functional 5-HT receptors in human occipital artery

    Verheggen, R., Meier, A., Wienekamp, A., Kruschat, T., Brattelid, Trond, Levy, Finn Olav (2004)
  • Functional 5-HT receptors in human occipital artery

    Verheggen, R., Meier, A., Wienekamp, A., Kruschat, T., Brattelid, Trond, Levy, Finn Olav (2004)
  • Cloning, pharmacological characterisation and tissue distribution of a novel 5-HT4 receptor splice variant, 5-HT4(i)

    Brattelid, Trond, Kvingedal, Ane Marit, Krobert, Kurt Allen, Andressen, Kjetil Wessel, Bach, Trond, Hystad, Marit Elise (2004)
  • Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failure

    Brattelid, Trond, Qvigstad, Eirik, Lynham, J.A., Molenaar, P., Aass, H., Geiran, Odd (2004)
  • Induction of 5-HT4 receptor mediated inotropic response to serotonin in failing ventricular myocardium

    Qvigstad, Eirik, Brattelid, Trond, Sjaastad, Ivar, Krobert, Kurt Allen, Sejersted, Ole M, Skomedal, Tor (2003)
  • Novel effect of serotonin (5-HT) in heart faiure. A new therapeutic agent?

    Qvigstad, Eirik, Brattelid, Trond, Sjaastad, Ivar, Krobert, Kurt Allen, Sejersted, Ole M, Skomedal, Tor (2003)
  • Regulation of serotonin receptor mRNA levels in heart failure

    Tveit, Kristine, Brattelid, Trond, Qvigstad, Eirik, Sjaastad, Ivar, Krobert, Kurt Allen, Sejersted, Ole M (2003)
  • Novel effects of serotonin in heart failure

    Qvigstad, Eirik, Brattelid, Trond, Sjaastad, Ivar, Krobert, Kurt Allen, Sejersted, Ole M, Skomedal, Tor (2003)
  • Induction of serotonin receptors and inotropic effects in heart failure: a potential new neurohormonal target?

    Qvigstad, Eirik, Brattelid, Trond, Sjaastad, Ivar, Krobert, Kurt Allen, Sejersted, Ole M, Skomedal, Tor (2003)
  • Novel effect of serotonin (5-HT) in heart failure. A new therapeutic target

    Qvigstad, Eirik, Brattelid, Trond, Sjaastad, Ivar, Krobert, Kurt Allen, Sejersted, Ole M, Skomedal, Tor (2003)
  • Stabilisering av fisk ved prosedyrer ute av vann

    Brattelid, Trond, Smith, Adrian John (2001)
  • 5-HT<SUB>4(a)</SUB> and 5-HT<SUB>4(b)</SUB> receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle

    Bach, Trond, Syversveen, Trygve, Kvingedal, Ane Marit, Krobert, Kurt Allen, Brattelid, Trond, Kaumann, Alberto Julio (2001)
  • Cardiac expression and pharmacological profile of human 5-HT<SUB>4</SUB> receptors

    Brattelid, Trond, Kvingedal, Ane Marit, Bach, Trond, Krobert, Kurt Allen, Kaumann, Alberto Julio, Levy, Finn Olav (2001)
  • Potential protein protein interactions with the unique intracellular carboxy tail of three 5-HT<SUB>4</SUB> receptor splice variants

    Brattelid, Trond, Kvingedal, Ane Marit, Bach, Trond, Krobert, Kurt Allen, Kaumann, Alberto Julio, Levy, Finn Olav (2001)
  • Refinement of fish research

    Brattelid, Trond, Smith, Adrian John, Engh, Espen, Needham, Jeff (2000)
  • Guidelines for reporting the results of fish experiments

    Brattelid, Trond, Smith, Adrian John (2000)
  • Methods of positioning fish for surgery or other procedures out of water

    Brattelid, Trond, Smith, Adrian John (2000)
  • Pharmacological and immunological characterisation of human 5-HT4 receptor splice variants

    Brattelid, Trond, Kvingedal, Ane Marit, Bach, Trond, Krobert, Kurt Allen, Kaumann, Alberto Julio, Levy, Finn Olav (2000)
  • Pharmacological characterisation and cardiac expression of known and novel human 5-HT4 receptor splice variants

    Brattelid, Trond, Kvingedal, Ane Marit, Bach, Trond, Krobert, Kurt Allen, Kaumann, Alberto Julio, Levy, Finn Olav (2000)
  • Pharmacological and immunological characterisation of human 5-HT4 receptor splice variants

    Brattelid, Trond, Kvingedal, Ane Marit, Bach, Trond, Krobert, Kurt Allen, Kaumann, Alberto Julio, Levy, Finn Olav (2000)
  • Forsøksdyrlære for fiskeforskere

    Brattelid, Trond (1999)