Førsteamanuensis

Alvhild Alette Bjørkum

Emeritus/emerita, FIN
Alvhild Alette Bjørkum
Tel: +47 55 58 76 27
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KRONSTAD, D312
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Arbeids- og kompetanseområde

  1. Jeg er søvnforsker og fysiolog/nevrofysiolog og forsker på fysiologiske- og cellebiologiske mekanismer som endres etter søvnmangel, forskjøvet søvn og simulert nattskiftarbeid. Jeg underviser i fagene anatomi, fysiologi og histologi samt cellebiologi der jeg ønsker å få studentene til å forstå fysiologiske- og cellebiologiske mekanismer og sammenhenger og kunne utrykke dette godt særlig skriftlig. Jeg har undervist og veiledet bachelor, master og PhD-studenter i pågående forskningsprosjekt siden 2002 der biologiske markører måles i ulike kroppsvæsker som blod og spytt/saliva etter søvnmangel og andre fenotyper av stress på kroppen.  

E-mail: Alvhild.Bjorkum@hvl.no and check out in Norwegian Bergen Søvn og Kronobiologisk Nettverk ; https://www.uib.no/fg/sc in English Bergen Sleep and Chronobiology Network; https://www.uib.no/en/rg/sc
Mobile +47 97673388

 CV: https://home.hvl.no/ansatte/aab/CV-47-NFR-mal 2022_CV.htm

 CV: ALVHILD ALETTE BJØRKUM (hvl.no)

 PubMed  https://www.ncbi.nlm.nih.gov/pubmed/?term=Bjorkum

 Web of Science http://apps.webofknowledge.com.galanga.hvl.no/Search.do?product=WOS&SID=F3Q1BshdDLhc7oX96xg&search_mode=GeneralSearch&prID=974e7ab4-70a2-459e-819d-1e9f6004f6fb 

Cristin – Current Research Information SysTem In Norway - Reseach database – Bjørkum, Alvhild*

https://wo.cristin.no/as/WebObjects/cristin.woa/wa/fres?action=sok&etternavn=bj%C3%B8rkum&fornavn=alvhild*&erNorsk=1&erNordisk=1&erNasjonalt=1&erInternasjonalt=1&erUkjent=1&visParametre=1&sort=ar&bs=50

 

www.hvl.no | twitter.com/hvl_no | facebook.com/hvl.no

 

 

 

 

 

Underviser i
  • Bio171 Anatomi, fysiologi og histologi
  • Bio174 Cellebiologi
  • Veileder Bachelor på egne FoU-prosjekt
  • Veileder internasjonale Master studenter på egne FoU-prosjekt
  • Veileder Master på egne og tverrfaglige FoU-prosjekt
  • Veileder PhD-kandidat/stipendiat på egne og tverrfaglige FoU-prosjekt
Forskar på
  • Søvn, søvnmangel, forskjøvet søvn og simulert nattskiftarbeid
  • Stress på celler etter endret søvn og andre fenotyper for stress
  • Fysiologiske- og cellebiologiske endringer etter endret søvn med proteomikk og systembiologi
Forskargrupper

Publikasjonar

  • In-Silico Prediction of Mechanical Behaviour of Uniform Gyroid Scaffolds Affected by Its Design Parameters for Bone Tissue Engineering Applications

    Nazimutheen Musthafa, Haja Sherief, Walker, Jason, Rahman, Talal, Bjørkum, Alvhild Alette, Mustafa, Kamal Babikeir Elnour, Velauthapillai, Dhayalan (2023)
    Computation 2023 Volum 11 ;(9)

  • Scientists Against War: A Plea to World Leaders for Better Governance

    Pandi-Perumal, Seithikurippu R., Kumar, Velayudhan Mohan, Pandian, Namasivayam Ganesh, de Jong, Joop T., Andiappan, Sudalaikannu, Corlateanu, Alexandru, Mahalaksmi, Arehally Marappa, Chidambaram, Saravana Babu, Kumar, Ramasamy Rajesh, Ramasubramanian, Chellamuthu, Sivasubramaniam, Sudhakar, Bjørkum, Alvhild Alette, Cutajar, JosAnn, Berk, Michael, Trakht, Ilya, Vrdoljak, Anton, Meira e Cruz, Miguel, Eyre, Harris A., Grønli, Janne, Cardinali, Dainiel P., Maercker, Andreas, van de Put, Willem A. C. M., Guzder, Jaswant, Bjorvatn, Bjørn, Tol, Wietse A., Acuña-Castroviejo, Darío, Meudec, Marie, Morin, Charles M., Partinen, Markku, Barbui, Corrado, Jordans, Mark J. D., Braakman, Mario H., Knaevelsrud, Christine, Pallesen, Ståle, Sijbrandij, Marit, Golombek, Diego Andrés, Espie, Colin A., Cuijpers, Pim, Agudelo, Hernán Andrés Marín, van der Velden, Koos, van der Kolk, Bessel A., Hobfoll, Stevan E., Devillé, Walter L. J. M., Gradisar, Michael, Riemann, Dieter, Axelsson, John, Benítez-King, Gloria, Macy, Robert D., Poberezhets, Vitalii, Hoole, Samuel Ratnajeevan Herbert, Murthy, Rangaswamy Srinivasa, Hegemann, Thomas, Heinz, Andreas, Salvage, Jane, McFarlane, Alexander C., Keukens, Rob, de Silva, Harendra, Oestereich, Cornelia, Wilhelm, Jochen, von Cranach, Michael, Hoffmann, Klaus, Klosinski, Matthias, Bhugra, Dinesh, Seeman, Mary V. (2022)
    Sleep and Vigilance 2022

  • Human blood serum proteome changes after 6 hours of sleep deprivation at night

    Bjørkum, Alvhild Alette, Duran, Ana Carrasco, Berven, Frode Steingrimsen, Roy, Dola Sinha, Rosendahl, Karen, Birkeland, Even, Stuhr, Linda Elin Birkhaug (2021)
    Sleep Science and Practice (SSP) 2021 Volum 5 ;(14)

  • Sleep measured by the Oura-ring before, during and after demanding situations/operations in the arctic waters

    Bjørkum, Alvhild Alette, Knutsen, Tiril, Lærdal, Kristina (2019)

  • Changes in human salivary proteome after six hours of sleep deprivation at night

    Bjørkum, Alvhild Alette, Frich Meling, Ingjerd, Kluge, Beate, Rosendahl, Karen (2018)

  • Fast hyperbaric decompression after heliox saturation altered the brain proteome in rats

    Bjørkum, Alvhild Alette, Oveland, Eystein, Stuhr, Linda Elin Birkhaug, Havnes, Marianne Bjordal, Berven, Frode, Grønning, Marit, Hope, Arvid (2017)
    PLOS ONE 2017 Volum 12 ;s. 1-16

  • Implementering av ny teknologi i offentlige forsknings- og helsemiljø med impedansspektroskopi som eksempel

    Kluge, Beate, Bjørkum, Alvhild Alette, Kvitastein, Olav Andreas (2016)

  • Classification of DNA sequences using support vector machines and autoencoders.

    Kristensen, Terje, Rostad, Kari, Bjørkum, Alvhild Alette, Hestetun, kristian (2016)

  • DNA classification of germs and carcinogenic virus using Support Vector Machine

    Kristensen, Terje, Rostad, Kari, Bjørkum, Alvhild Alette, Karlsen, Markus Lippert (2016)

  • MRI of the central nervous system in rats following heliox saturation decompression

    Hope, Arvid, Stuhr, Linda Elin Birkhaug, Pavlin, Tina, Bjørkum, Alvhild Alette, Grønning, Marit (2015)
    Undersea & Hyperbaric Medicine 2015 Volum 42 ;(1)s. 57-64

  • Can a Computer Learn to Recognize DNA Sequences?

    Kristensen, Terje, Bjørkum, Alvhild Alette, Rostad, Kari, Hestetun, kristian, Karlsen, Markus Lippert (2015)

  • Proteomic Changes in Human Blood Serum after Sleep Deprivation

    Bjørkum, Alvhild Alette, Sinha Roy, Dola, Duran, Ana Carrasco, Kristensen, Terje, Kluge, Beate, Rosendahl, Karen (2014)

  • Data Clustering with Visualization of Proteomics Data

    Kristensen, Terje, Jakobsen, Vemund, Bjørkum, Alvhild Alette (2014)

  • Safety in pediatric imaging: an update

    Arthurs, Owen John, Bjørkum, Alvhild Alette (2013)
    Acta Radiologica 2013 Volum 54 ;(9)s. 983-990

  • Pedriatic MRI-safety revisited

    Bjørkum, Alvhild Alette, Rosendahl, Karen, Arthurs, Owen J. (2013)
    Pediatric Radiology 2013 Volum 43 ;

  • Søvn påvirker hukommelse og helse. Kan cellene våre bli stresset av søvnmangel? Kan det måles?

    (2012)

  • PROTEIN IDENTIFICATION AND CHANGED PROTEIN LEVELS AFTER SLEEP DEPRIVATION

    Bjørkum, Alvhild Alette, Nygård, Irene, Braseth, Turid Aarhus, Kristensen, T, Kluge, Beate, Rosendahl, Karen (2012)
    Sleep 2012 Volum 35 ;

  • Protein-ID and changed protein levels by proteomics in human blood serum after sleep deprivation

    Bjørkum, Alvhild Alette, Gurvin, Ingmund, Braseth, Turid Aarhus, Nygård, Irene, Rosendahl, K (2011)

  • Protein Identification and Changed Protein Levals after Sleep Deprivation

    Bjørkum, Alvhild Alette, Gurvin, Ingmund, Nygård, Irene, Braseth, Turid Aarhus, Kristensen, Terje, Kluge, B, Rosendahl, K (2011)

  • Søvnmangel ved skift- og nattarbeid. Hvordan påvirker det kroppen

    (2010)

  • Søvnmangel ved skift- og nattarbeid. Hvordan påvirker det kroppen

    (2010)

  • Protein identification of changed protein levels by proteomics after sleep restriction

    Bjørkum, Alvhild Alette, Gurvin, Ingmund, Braseth, Turid Aarhus, Nygård, Irene, Kristensen, Terje, Kluge, B, Rosendahl, K (2010)

  • Protein identification and changed levels by proteomics after sleep deprivation

    Bjørkum, Alvhild Alette, Gurvin, Ingmund, Braseth, Turid Aarhus, Nygård, Irene, Rosendahl, K (2010)

  • Simulation of biological networks - a multiagent (MAS) framework

    Kristensen, Terje, Bjørkum, Alvhild Alette (2010)

  • Different visualization schemes of protein data clustering

    Kristensen, Terje, Jakobsen, Vemund, Bjørkum, Alvhild Alette (2010)

  • Data protein clustering - some adaptive algorithms

    Kristensen, Terje, Jakobsen, Vemund, Bjørkum, Alvhild Alette, Kluge, B (2010)

  • Matrix metalloproteinase-9 activity increased by two different types of epileptic seizures that do not induce neuronal death: A possible role in homeostatic synaptic plasticity

    Takacs, Eszter, Nyilas, Rita, Szepesi, Zsuzsanna, Baracskay, Peter, Karlsen, Bente, Røsvold, Tina, Bjørkum, Alvhild Alette, Czurco, Andras, Kovacs, Zsolt, Kékesi, Adrienna K., Juhasz, Gabor, Juhász, Gábor (2010)
    Neurochemistry International 2010 Volum 56 ;s. 799-809

  • Human serum protein profile and protein identification after sleep restriction

    Bjørkum, Alvhild Alette, Braseth, Turid Aarhus, Nygaard, Inger, Gurvin, Ingmund, Kristensen, Terje, Nybø, Roar, Kluge, B, Rosendahl, K (2009)

  • Proteomic and Genomic Changes after Routine Magnetic Resonance Imaging (MRI) in children. A Pilot Study

    Bjørkum, Alvhild Alette, Kluge, B, Myhre, C, Rosendahl, K (2009)

  • Computational Proteomics - a pattern solutions approach

    Kristensen, Terje, Jakobsen, Vemund, Bjørkum, Alvhild Alette (2009)

  • Human serum protein profile after sleep restriction

    Bjørkum, Alvhild Alette, Nygaard, Inger, Braseth, Turid Aarhus, Gurvin, Ingmund, Kristensen, Terje, Nybø, Roar, Rosendahl, Karen, Kluge, Beate (2008)
    Journal of Sleep Research 2008 Volum 17 ;s. 5-5

  • Human serum protein profile after sleep

    Bjørkum, Alvhild Alette, Nygaard, Inger, Braseth, Turid Aarhus, Gurvin, Ingmund, Kristensen, T, Nybø, Roar, Rosendahl, K, Kluge, B (2008)
    Journal of Sleep Research 2008

  • Increased extracellular 5-HT but no change in sleep after perfusion of a 5-HT1A antagonist into the dorsal raphe nucleus of rats

    Fiske, E, Portas, Chiara M, Grønli, J, Sørensen, E, Bjorvatn, B, Bjørkum, Alvhild Alette, Ursin, R (2008)
    Acta Physiologica 2008 Volum 193 ;(1)s. 89-97

  • Increased extracellular 5-HT but no change in sleep after perfusion of a 5-HT1A antagonist into the dorsal raphe nucleus of rats

    Fiske, Eldbjørg, Portas, Chiara Maria, Grønli, Janne, Sørensen, Eli, Bjorvatn, Bjørn, Bjørkum, Alvhild Alette, Ursin, Reidun (2008)
    Acta Physiologica 2008 Volum 193 ;(1)s. 89-97

  • Rapid eye movement (REM) sleep homeostatic regulatory processes in the rat: Changes in the sleep-wake stages and electroencephalographic power spectra

    Shea, JL, Mochizuki, T, Sagvaag, Vivian, Aspevik, Tone, Bjørkum, Alvhild Alette, Datta, S (2008)
    Brain Research 2008 Volum 1213 ;s. 48-56

  • In å sove alene

    (2007)

  • Nattarbeid på helsa løs

    (2007)

  • Stress på cellenivå. Ukens ugle

    (2007)
    Bergens Tidende 2007

  • Søvnløshet er verst for B-mennesker. Kommentar

    (2007)

  • Changed Protein Profile after Sleep Restriction

    Bjørkum, Alvhild Alette, Kluge, B, Braseth, Turid Aarhus, Gurvin, Ingmund, Kristensen, Terje, Nybø, Roar, Rosendahl, K, Nygaard, Inger (2007)
    Sleep and Biological Rhythms 2007

  • Increased extracellular 5-HT but no change of sleep after perfusion of a 5-HT1A antagonist into the dorsal raphe nucleous of rats

    Fiske, Eldbjørg, Portas, Chiara Maria, Grønli, Janne, Sørensen, Eli, Bjorvatn, Bjørn, Bjørkum, Alvhild Alette, Ursin, Reidun (2007)
    Acta Physiologica 2007

  • Forskning på søvn, skiftarbeid og stressa celler - bioteknologiske muligheter

    (2006)

  • Livsviktig søvn?

    (2006)

  • S mye søvn trenger du

    (2006)

  • Skiftarbeid kan gi kreft, kommentar

    (2006)

  • Sunn helse og skiftarbeid

    (2006)

  • Søvn

    (2006)

  • Søvn, søvnmangel,skiftarbeid

    (2006)

  • Differential expression proteomics after sleep deprivation

    Bjørkum, Alvhild Alette, Rosendahl, K, Braseth, Turid Aarhus, Nygård, Irene, Gurvin, Ingmund, Kristensen, Terje, Nybø, Roar (2006)
    Journal of Sleep Research 2006s. 238-239

  • Differential expression proteomics after sleep deprivation

    Bjørkum, Alvhild Alette, Rosendahl, Karen, Braseth, Turid Aarhus, Nygård, Irene, Gurvin, Ingmund, Kristensen, Terje, Nybø, Roar (2006)
    Journal of Sleep Research 2006 Volum 15 ;s. 238-239

  • Høy pris for skiftarbeid

    (2005)

  • Søvn og biologiske rytmer

    (2005)

  • Søvn og stressa celler

    (2005)

  • Søvnforskerne fra Seljedalen

    (2005)

  • Turnusarbeid - søvn og biologiske rytmer

    (2005)

  • Cellular response to MR-procedure

    Bjørkum, Alvhild Alette, Helgesen, Carsten (2005)

  • Proteome expression changes in human blood serum after sleep deprivation by a decision tree classification method

    Bjørkum, Alvhild Alette, Kristensen, Terje, Rosendahl, K, Holm, I, Kirkevoll, M, Kroksveen, AC, Sæterdal, EK, Nybø, Roar, Kanhema, T.T., Kluge, B, Bjørnstad, A (2005)

  • Sleep deprivation changes proteome expression

    Bjørkum, Alvhild Alette, Rosendahl, K, Ingebrigtsen, H.B., Kolstad, H, Myhr, I M, Alvsvaag, S K, Stange, E, Kanhema, T.T., Kluge, B, Bjørnstad, A (2005)

  • Sleep deprivation changes proteome expression

    Bjørkum, Alvhild Alette, Rosendahl, Karen, Ingebrigtsen, HB, Kolstad, H, Myhr, IM, Alvsvaag, SE, Stange, E, Kanhema, Tambudzai, Kluge, Beate, Bjørnstad, A (2005)
    Sleep 2005 Volum 28 ;

  • Decision trees indentifying changes in proteome expression induced by sleep deprivation

    Kristensen, Terje, Nybø, Roar, Bjørkum, Alvhild Alette (2005)

  • Decision trees indentifying changes in proteome expression induced by sleep deprivation

    Kristensen, Terje, Nybø, Roar, Bjørkum, Alvhild Alette (2005)

  • Skiftarbeid og helse

    (2004)

  • Skiftarbeid og ulykker

    (2004)

  • Sleep deprivation - consequences for proteome expression. Accepted abstract to the 17th Congress of the European Sleep Research Society

    (2004)

  • Søvn - fra stress til sykdom, intervju ved Jill Johannessen

    (2004)

  • Søvn og biologiske rytmer

    (2004)

  • Søvn, skiftarbeid og helse

    (2004)

  • Søvnforskere reagerer, intervju

    (2004)

  • Tropevarme og søvn, intervju i temaartikkel

    (2004)

  • Uten søvn blir du syk, intervju ved Ingvill Eriksen

    (2004)

  • Skiftarbeid og ulykker - relevans for offshoreindustrien

    Bjørkum, Alvhild Alette, Pallesen, Ståle, Holsten, F, Bjorvatn, Bjørn, Holsten, Fred (2004)
    Tidsskrift for Den norske legeforening 2004 Volum 124 ;(21)s. 2773-2775

  • Skiftarbeid og ulykker - relevans for offshoreindustrien

    Bjørkum, Alvhild Alette, Pallesen, Ståle, Holsten, Fred, Bjorvatn, Bjørn (2004)
    Tidsskrift for Den norske legeforening 2004 Volum 124 ;(21)s. 2773-2775

  • Innføring i DNA-teknologi for bioingeniører våren 2004

    Daae, Frida Lise, Bjørkum, Alvhild Alette (2004)

  • Er søvnvansker ved nattarbeid et problem for offshoreindustrien?

    Pallesen, Ståle, Holsten, Fred, Bjørkum, Alvhild Alette, Bjorvatn, Bjørn (2004)
    Tidsskrift for Den norske legeforening 2004 Volum 124 ;(21)s. 2070-2072

  • Søvnvansker ved nattarbeid, et problem for offshoreindustrien?

    Pallesen, Ståle, Holsten, Fred, Bjørkum, Alvhild Alette, Bjorvatn, Bjørn (2004)
    Tidsskrift for Den norske legeforening 2004 Volum 124 ;(21)s. 2770-2772

  • Effect of bicuculline perfused in DRN on 5-HT levels in the DRN and FC

    (2003)
    Sleep 2003

  • Poster P4 Proteome Expression after Sleep Deprivation

    (2003)

  • Change in the Genome and the Proteome after Sleep Deprivation

    Bjørkum, Alvhild Alette, Bjørkum, Alvhild Alette, Kanhema, T.T. (2003)

  • Change in the Genome and the Proteome after Sleep Deprivation

    Bjørkum, Alvhild Alette, Kanhema, T.T. (2003)

  • Perfusion of a 5-HT1A Antagonist in the Cat DRN Increases Wakefulness and Extracellular 5-HT Level in DRN

    Bjørkum, Alvhild Alette, Strecker, Robert E, Portas, Chiara M, Porkka-Heiskanen, Tarja, Thakkar, Mahesh, McCarley, Robert W (2003)
    Sleep Research Online 2003 Volum 5 ;(4)s. 149-154

  • Perfusion of a 5-HT1A antagonist in the cat DRN increases wakefulness and extracellular 5-HT level in DRN

    Bjørkum, Alvhild Alette, Strecker, Robert E, Portas, Chiara Maria, Porkka-Heiskanen, Tarja, Thakkar, Mahesh, McCarley, Robert W (2003)
    Sleep Research Online 2003 Volum 5 ;(4)s. 149-154

  • Effect of bicuculline perfused in DRN on 5-HT levels in the DRN and FC

    Fiske, Eldbjørg, Grønli, Janne, Hamre, Frøydis, Bjørkum, Alvhild Alette, Portas, Chiara Maria, Ursin, Reidun (2003)

  • Effects of sleep deprivation on extracellular serotonin in the hippocampus and frontal cortex of the rat

    Bjorvatn, Bjørn, Grønli, Janne, Hamre, Frøydis, Sørensen, Eli, Fiske, Eldbjørg, Bjørkum, Alvhild Alette, Portas, Chiara Maria, Ursin, Reidun (2002)
    Neuroscience 2002 Volum 113 ;(2)s. 323-330

  • Afferents to the ventrolateral preotic nucleus : Chou,T., Bjørkum,A.A.,Lu,J.,Scammell, T. and Saper,C.B

    (2002)
    ? 2002 Volum 22 ;(3)s. 977-990

  • Effects of sleep deprivation on extracellular serotonin and frontal cortex of the rat : Bjorvatn,B.,Grønli,J.,Hamre,F.,Sørensen,E.,Fiske,,E., Bjørkum,A.A., Portas,C.M., and Ursin,R

    (2002)
    Neuroscience 2002 Volum 113 ;(2)

  • Investigation of the effect of bicuculline perfused in DRN on sleep, waking and 5-HT levels in the DRN and FC

    (2002)

  • Selective activation of extended ventrolateral preoptic nucleus during rapid eye movement sleep : Lu,J.,Bjørkum,A.A.,Xu,M.,Gaus,S.E., Shiromani,P. and Saper,C.B

    (2002)
    Journal of Neuroscience 2002 Volum 22 ;(11)s. 4568-4576

  • Afferents to the Ventrolateral Preoptic Nucleus

    Chou, Thomas C., Bjørkum, Alvhild Alette, Lu, Jun, Scammell, Thomas E., Saper, Clifford B. (2002)
    Journal of Neuroscience 2002 Volum 22 ;(3)s. 977-990

  • Investigation of the effect of bicuculline perfused in DRN on sleep, waking and 5-HT levels in the DRN and FC

    Fiske, Eldbjørg, Grønli, Janne, Hamre, Frøydis, Bjørkum, Alvhild Alette, Portas, Chiara Maria, Ursin, Reidun (2002)

  • Selective activation of the extended ventrolateral preoptic nucleus during rapid eye movement sleep

    Lu, Jun, Bjørkum, Alvhild Alette, Xu, Man, Gaus, Stephanie E., Shiromani, Priyattam J., Saper, Clifford B. (2002)
    Journal of Neuroscience 2002 Volum 22 ;(11)s. 4568-4576

  • Effects of sleep deprivation on extracellular serotonin in the hippocampus and frontal cortex of the rat

    Bjorvatn, Bjørn, Grønli, Janne, Hamre, Frøydis, Sørensen, Eli, Fiske, Eldbjørg, Bjørkum, Alvhild Alette, Portas, Chiara Maria, Ursin, Reidun (2001)

  • Role of serotonin in REM sleep mechanisms - preclinical evidence

    (2001)

  • Sleep and waking following microdialysis perfusion of the selective 5-HT 1A receptor antagonist p-MPPI into the dorsal raphe nucleus in the freely moving rat

    Sørensen, Eli, Grønli, Janne, Bjorvatn, Bjørn, Bjørkum, Alvhild Alette, Ursin, Reidun (2001)
    Brain Research 2001 Volum 897 ;s. 122-130

  • Basic regulatory mechanisms of the serotonergic system in sleep and depression

    (2000)

  • Basic sleep research - Glimpse of past present and future

    (2000)

  • Raphe nuclei and the ventrolateral preoptic nucleus

    (2000)

  • Microdialysis perfusion of 5-HT-1a receptor ago- and anagonists in dorsal raphe nucleus - changes in 5-HT levels and behavioral state

    Bjørkum, Alvhild Alette, Portas, Chiara Maria, Bjorvatn, Bjørn, Sørensen, Eli, Ursin, Reidun (2000)

  • Dialysis perfusion of a 5-HT1A receptor antagonist in dorsal raphe nucleus increases 5-HT levels in sleep and waking

    Bjørkum, Alvhild Alette, Portas, CM, Bjorvatn, Bjørn, Sørensen, Eli, Grønli, Janne, Ursin, Reidun (2000)

  • Microdialysis perfusion of a 5-HT1A receptor antagonist in dorsal raphe nucleus change 5-HT levels in sleep and waking

    Bjørkum, Alvhild Alette, Portas, CM, Bjorvatn, Bjørn, Sørensen, Eli, Grønli, Janne, Ursin, Reidun (2000)

  • Micodialysis perfusion of 5-HT1A receptor ago- and antagonists in dorsal raphe nucleus - changes in 5-HT levels and behaviorial state

    Bjørkum, Alvhild Alette, Portas, CM, Bjorvatn, Bjørn, Sørensen, Eli, Ursin, Reidun (2000)

  • What does c-fos tell us about sleep and wake active areas in the brain - supporting old and creating new hypotheses?

    Bjørkum, Alvhild Alette, Saper, Clifford B (2000)

  • What to prefer and why: Microdialysis versus microinjections in in vivo sleep-wake studies

    Bjørkum, Alvhild Alette, Saper, Clifford B, McCarley, Robert W (2000)

  • Long term effects of cholinergic lesion of the nucleus of the diagonal band of broca: Sleep-wake EEG/EMG recordings in rats

    de Lacalle, S, Bjørkum, Alvhild Alette (2000)

  • Sleep and waking following perfusion of a selective 5-HT1A antagonist in the dorsal raphe nucleus in rats

    Sørensen, Eli, Bjorvatn, Bjørn, Bjørkum, Alvhild Alette, Ursin, Reidun (2000)

  • Sleep and waking following perfusion of a selective 5-HT-1a antagonist in the dorsal raphe nucleus in rats

    Sørensen, Eli, Bjorvatn, Bjørn, Bjørkum, Alvhild Alette, Ursin, Reidun (2000)

  • A single dose of the adenosine A1 antagonist 8-cyclopentyl-theofylline (CPT) increases hippocampal serotonin during waking in rats as measured by microdialysis

    Ursin, Reidun, Grønli, Janne, Sørensen, Eli, Bjørkum, Alvhild Alette, Bjorvatn, Bjørn (2000)

  • Long term sleep-wake EEG/EMG recordings in rats after unilateral intraparenchymal infusion of specific cholinergic toxin 192 IgG-saporin into the diagonal band of broca

    Bjørkum, Alvhild Alette, de Lacalle, S (1999)

  • Afferents to and efferents from the raphe nuclei to the ventrolateral preoptic nucleus

    Bjørkum, Alvhild Alette, Ha, Q H, Saper, Clifford B (1999)

  • Connections between the raphe nucleus and the ventrolateral preoptic nucleus

    Bjørkum, Alvhild Alette, Ha, Q H, Saper, Clifford B (1999)

  • Behavioral state-related changes of extracellular serotonin consentration in the pedunculopintine tegmental nucleus: A microdialysis study in freely moving animals

    Strecker, RE, Thakkar, MM, Porkka-Heiskanen, T, Dauphin, LJ, Bjørkum, Alvhild Alette, McCarley, RW (1999)
    Sleep 1999 Volum 2 ;(2)s. 21-27

  • A microdialysis study of neurotransmitters/neuromodulators regulating dorsal raphe nucleus activity; serotonin, GABA and adenosine

    (1998)

  • A microdialysis study of neurotransmitters/neuromodulators regulating dorsal raphe nucleus activity: serotonin, GABA and adenosine

    (1998)

  • Perfusion by microdialysis of a 5-HT1A receptor antagonist in dorsal raphe nucleus increases 5-HT levels in sleep and waking

    Bjørkum, Alvhild Alette, Portas, CM, Bjorvatn, Bjørn, Sørensen, Eli, Grønli, Janne, Ursin, Reidun (1998)

  • Modulatory role of the descending serotonergic system in sleep and waking

    Bjørkum, Alvhild Alette, Bjorvatn, Bjørn, Neckelmann, Dag, Ursin, Reidun (1997)

  • Serotonin and GABA inhibit dorsal raphe nucleus and increase REM sleep as revealed by microdialysis

    Bjørkum, Alvhild Alette, Porkka-Heiskanen, T, Portas, CM, Strecker, RE, Stenberg, D, McCarley, RW (1997)

  • GABA modulates the dorsal raphe and alters the pattern of sleep-waking

    Bjørkum, Alvhild Alette, Strecker, RE, Porkka-Heiskanen, T, Stenberg, D, McCarley, RW (1997)

  • Adenosine: A mediator of the sleep-inducing effects of prolonged wakefulness

    Porkka-Heiskanen, Tarja, Strecker, Robert E, Thakkar, Mahesh, Bjørkum, Alvhild Alette, Greene, RW, McCarley, Robert W. (1997)
    Science 1997 Volum 276 ;(5316)s. 1265-1268

  • Hypothermia and the 5-HT syndrome induced by CGS 12066B, independently of 5-HT(1B) receptor activation

    Bjorvatn, Bjørn, Neckelmann, Dag, Bjørkum, Alvhild Alette, Ursin, Reidun (1996)
    Behavioural Pharmacology 1996 Volum 7 ;s. 462-469

  • Modulatory role of the descending serotonergic system in sleep and waking

    (1996)
    Universitetet i Bergen. Isbn: 82-90952-17-1

  • Sleep/waking effects following intrathecal administration of the 5-HT(1A) Agonist 8-OH-DPAT alone and in combination with the putative 5-HT(1A) antagonist NAN-190 in rats

    Bjørkum, Alvhild Alette, Ursin, Reidun (1996)
    Brain Research Bulletin 1996 Volum 39 ;(6)s. 373-379

  • Citalopram: differential sleep/wake and EEG power spectrum effects after single dose and chronic administration

    Neckelmann, Dag, Bjorvatn, Bjørn, Bjørkum, Alvhild Alette, Ursin, Reidun (1996)
    Behavioural Brain Research 1996 Volum 79 ;s. 183-192

  • Sleep and EEG power spectral effects of the 5-HT(1A) agonist/antagonist NAN-190 alone and in combination with citalopram

    Neckelmann, Dag, Bjørkum, Alvhild Alette, Bjorvatn, Bjørn, Ursin, Reidun (1996)
    Behavioural Brain Research 1996 Volum 75 ;s. 159-168

  • Sleep/Waking and EEG Power Spectrum Effects of a Nonselective Serotonin (5-HT) Antagonist and a Selective 5-HT Reuptake Inhibitor Given Alone and in Combination

    Bjorvatn, Bjørn, Bjørkum, Alvhild Alette, Neckelmann, Dag Olav Grini, Ursin, Reidun (1995)
    Sleep 1995 Volum 18 ;(6)s. 451-462